Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. There have been some cases of unusual cancers, some resulting in death, reported in children and teenage patients who started using tumor necrosis factor (TNF) blockers before 18 years of age. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB. Some patients have died from these infections. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Serious infections have happened in patients taking ENBREL. ENBREL can lower the ability of your immune system to fight infections. What is the most important information I should know about ENBREL?ĮNBREL is a medicine that affects your immune system. I’ve been given a gift, and I’m truly, truly grateful for it. I hope someday I can be half the mom that she is.īrandy: To hold that baby, it just means everything to me. Shayla: My mom is really kind of incredible. I get to have an impact on my granddaughter. I get to have an impact on the rheumatoid arthritis community. Back then, I thought I was out of options, but I do have options. She became a special education teacher so that she could advocate for students and parents who need some extra support like she does.īrandy: I have this amazing career, and I have the ability to reach out to at-risk kids and make connections with them. Shayla: My mom has achieved a great deal in her life. Every day, I could do a little bit more, go a little bit farther. That allowed me to be more active in my own life, more active as a mom, more active as a teacher. Every day that went by, I hurt a little bit less. He started me out on ENBREL, and slowly things started to change. My doctor at the time suggested this new class of medication that had just been FDA approved. She used to tell us that it felt like there was pieces of glass in her wrist.īrandy: I was desperate to find something that would work effectively. Shayla: When I was little, we just knew that we had to be careful when we were playing with our mom. Additional Important Safety Information will be discussed later in this video. It was hard.ĮNBREL can cause serious side effects including: new infections or worsening of infections you already have, lymphoma and other types of cancer hepatitis B can become active if you already had it nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes blood problems (some fatal) new or worsening heart failure new or worsening psoriasis allergic reactions autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis. It was all I could do to take care of my children, and a lot of that was from the couch. Like, my family was afraid to hug me because it hurt. Every joint, from neck to toe, was in pain 24/7. I didn’t trust my hands enough to pick up my son. More importantly, reducing the inflammation helps stop the progression of permanent joint damage in moderate to severe RA and PsA, and helps psoriasis plaques get clearer in PsA.Īsk your doctor if ENBREL is right for you.īrandy: My kids grew up with a sick mom, a mom that couldn’t do everything. And by lessening the number of active TNF proteins, ENBREL helps reduce symptoms such as swelling, stiffness, and joint pain. ENBREL attaches itself to the TNF proteins to help block their activity. That means it's made from living things, like cells. Also, with PsA, the excessive TNF causes inflammation under the skin, which leads to the red itchy patches on the surface of the skin called plaques of psoriasis.ĮNBREL is a type of medicine known as a biologic. This inflammation can lead to joint pain, stiffness, even fatigue, and as time goes by that inflammation can wear down your cartilage and bone in your joints, causing irreversible joint damage. Too much TNF in your body causes inflammation in your joints. It creates too many proteins, one of which is tumor necrosis factor (TNF). Your immune system protects your body from infection and disease, but with moderate to severe rheumatoid arthritis (RA) and psoriatic arthritis (PsA) your immune system isn’t working properly. Enbrel ® (etanercept) is indicated for the treatment for patients with moderately to severely active rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, moderate to severe plaque psoriasis in adults and children 4 years and older, and moderately to severely active polyarticular juvenile idiopathic arthritis.
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